This looks like your family but Louisa was born in Kentucky. I assume from the census that this is James second marriage because William Holman 20 (b 1860) would make Louisa 10 when he was born.


1880 United States Federal Census
Name: Louisa Holman
Age: 30
Birth Year: abt 1850
Birthplace: Kentucky
Home in 1880: Dover, Lafayette, Missouri
Race: White
Gender: Female
Relation to Head of House: Wife
Marital Status: Married
Spouse's Name: James Holman
Father's Birthplace: Virginia
Mother's Birthplace: Tennessee
Occupation: Keeping House

James Holman 44
Louisa Holman 30
William Holman 20
Charles Holman 15
Bluford Holman 10
George Holman 8
Martha Holman 6
Harrison Holman 3
Robert Holman 8m

In the 1920 census Louisa is spelt Luzahn Holman 70 but the census name is difficult to read. In 1900 it is Lucy Holman 51. In 1910 it is Luzann Holdman [Luyam Holdman] again difficult to read. We need to know her real christen name, do you have a death registration?

I found these two marriages in right time period but again they were difficult to read. I think it looked more like the first entry.

Missouri, Marriages, 1750-1920"
groom's name: James Holman
bride's name: Liewtisia Senter
marriage date: 16 May 1873
marriage place: Mcdonald,Missouri
indexing project (batch) number: M51535-1
system origin: Missouri-ODM
source film number: 930075

Missouri Marriage Records, 1805-2002
Name: James Holman
Marriage Date: 16 May 1873
Marriage County: McDonald
Spouse Name: Deinlina Senton